N4-Methylcytidine is a nucleoside analogue that inhibits synthesis of human mitochondrial DNA by inhibiting bacterial enzyme uridine-cytidine kinase, which converts uridine to cytidine in the mitochondria. N4-Methylcytidine has been shown to be potent against viruses such as HIV and herpes simplex virus type 1 (HSV-1) in cell culture studies. This antiviral effect is due to the interference with viral dna replication and protein synthesis by preventing incorporation of uracil into dna and ribosomal RNA. Please contact us for GMP-grade inquiries.
Products > Nucleoside, Nucleotide, Phosphoramidite > Nucleosides | Products > Nucleoside, Nucleotide, Phosphoramidite > Nucleosides > Modified Nucleoside
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