Fludarabine

Overview

Fludarabine is a purine nucleoside derivative that disrupts ribonucleotide reductase and DNA polymerase in blood cells. Fludarabine exhibits antiproliferative activity (IC50 = 1.54 μM in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP, and survivin expression. Fludarabine displays anticancer activity against human hematological malignancies in vivo. Please contact us for GMP-grade inquiries.

Application

Products > Nucleoside, Nucleotide, Phosphoramidite > Nucleosides | Products > Nucleoside, Nucleotide, Phosphoramidite > Nucleosides > Fluoro-Modified Nucleosides

Product Information

• Catalog No.: BP-55389
• CAS No.: 21679-14-1
• Molecular Formula: C10H12FN5O4
• Molecular Weight: 285.2
• Storage: -20°C
• Availability: In Stock

Source

Original product source