Boc-Val-Ala-PAB-PNP

Overview

Boc-Val-Ala-PAB-PNB is a cleavable peptide ADC linker. The Val-Ala will specifically be cleaved by Cathepsin B. Since this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. PNP can be substituted by amine-bearing molecules.

Application

Products > PEG Linkers > GGFG Linkers | Products > ADC Linker, ADC Payload > Cleavable Linkers > Val-Ala

Product Information

• Catalog No.: BP-27986
• CAS No.: 1884578-00-0
• Molecular Formula: C27H34N4O9
• Molecular Weight: 558.6
• Storage: -20°C
• Availability: In Stock

Source

Original product source