Duocarmycin DM

Overview

Duocarmycin DM is a DNA minor-groove alkylator used as a cytotoxic payload in antibody-drug conjugates (ADCs). Its anticancer activity arises from a curved indole-based structure and a reactive spirocyclopropylcyclohexadienone electrophile, enabling sequence-selective DNA alkylation.

Application

Products > ADC Linker, ADC Payload > ADC Payload | Products > ADC Linker, ADC Payload > ADC Payload > Duocarmycin

Product Information

• Catalog No.: BP-43666
• CAS No.: 1116745-06-2
• Molecular Formula: C26H26ClN3O3
• Molecular Weight: 464
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source