OTX 015

Overview

OTX-015 is a selective BRD2, BRD3, and BRD4 inhibitor and inhibits the binding of BRD2, BRD3, and BRD4 to AcH4. OTX-015 has shown inhibition of BRD2, BRD3, and BRD4 with IC50 values are in the range 92 - 112 nM. OTX 015 displays antiproliferative effects at a sub-micromolar range in vitro in a wide range of solid tumor types and leukemias, downregulating c-Myc expression and inducing cell cycle arrest and apoptosis. Please contact us for GMP-grade inquiries.

Application

Products > PROTAC, Molecular glue > Inhibitors

Product Information

• Catalog No.: BP-25368
• CAS No.: 202590-98-5
• Molecular Formula: C25H22ClN5O2S
• Molecular Weight: 492
• Storage: -20°C
• Availability: In Stock

Source

Original product source