Brincidofovir

Overview

Brincidofovir is a prodrug of the acyclic nucleoside phosphonate cidofovir, which is converted to cidofovir in human lung fibroblasts. It effectively inhibits replication of CMV, HSV-1, HSV-2, cowpox, and vaccinia viruses, with EC50 values ranging from 0.0009 to ~1 µM. Brincidofovir also reduces mortality in mouse models of cowpox and vaccinia infections at doses of 6.7 and 5 mg/kg, respectively.

Application

PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Phospholipid | Drug Delivery, Surface Modification > Lipid Molecules > Phospholipid | Products > Lipids In Drug Delivery > Phospholipid | Products > Lipids In Drug Delivery > Phospholipid > Phosphate

Product Information

• Catalog No.: BP-42543
• CAS No.: 444805-28-1
• Molecular Formula: C27H52N3O7P
• Molecular Weight: 561.7
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source