Mc-Val-Cit-PAB-Cl

Overview

Mc-Val-Cit-PAB-Cl is a cleavable ADC linker . Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC 50 s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay).

Application

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Product Information

• Catalog No.: HY-112099
• CAS No.: 1639351-92-0
• Molecular Formula: C28H39ClN6O6
• Molecular Weight: 591.10
• Purity: 95.0%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source