CL4H6

Overview

CL4H6, an ionizable cationic amino lipid with an apparent pKa of 6.35, has been utilized in creating lipid nanoparticles (LNPs). LNPs incorporating CL4H6 and carrying siRNA for Factor VII reduction in mice's liver levels and tumor-targeting siRNAs for CD45, STAT3, and HIF-1alpha in OS-RC-2 renal cancer mouse xenograft models demonstrate tumor volume reduction.

Application

Products > Lipids In Drug Delivery > Advanced Lipid | Products > Lipids In Drug Delivery > Advanced Lipid > Advanced Lipid

Product Information

• Catalog No.: BP-40859
• CAS No.: 2256087-35-9
• Molecular Formula: C59H113NO5
• Molecular Weight: 916.6
• Storage: -20°C
• Availability: In Stock

Source

Original product source