Exatecan

Overview

Exatecan CAS:171335-80-1 is an innovative camptothecin (CPT) analog that demonstrates powerful topoisomerase-I inhibitory and antitumor activities. Its unique structure makes it highly effective against P-glycoprotein (P-gp) mediated multi-drug resistant cells, overcoming a major challenge in cancer therapy. Several Exatecan derivative-based antibody-drug and peptide-drug conjugate payloads exhibit impressive therapeutic indices across a broad spectrum of solid tumors. As a result, Exatecan is paving the way for the development of more effective and targeted cancer treatments, offering new hope for patients battling resistant malignancies.

Application

Payloads and Linker modified Payloads

Product Information

• Catalog No.: AP15197
• CAS No.: 171335-80-1
• Molecular Formula: C24H22FN3O4
• Molecular Weight: 435.45
• Purity: ≥98%
• Availability: In Stock

Source

Original product source