Safingol

Overview

Safingol is the L-threo diastereomer of D-erythro-sphinganine and a dual inhibitor of PKC and sphingosine kinase (SPHK). It inhibits PKC by binding to the regulatory phorbol-binding domain (IC50 = 24 µM) and also inhibits SPHK (Ki ≈ 5 µM).

Application

Products > Lipids In Drug Delivery > Sphingolipids | Products > Lipids In Drug Delivery > Sphingolipids > Sphinganine

Product Information

• Catalog No.: BP-42313
• CAS No.: 15639-50-6
• Molecular Formula: C18H39NO2
• Molecular Weight: 301.5
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source