SIAIS178

Overview

SIAIS178 represents an innovative proteolysis-targeting chimeric (PROTAC) degrader—a unique hybrid molecule intertwining the BCR-ABL kinase inhibitor dasatinib with a ligand designed for the Von Hippel-Lindau (VHL) E3 ubiquitin ligase through an optimized linker. It effectively directs the BCR-ABL protein for degradation through VHL-mediated mechanisms. Reagent-grade; for laboratory research purposes only.

Application

Products > PROTAC, Molecular glue > Degraders

Product Information

• Catalog No.: BP-41597
• CAS No.: 2376047-73-1
• Molecular Formula: C50H62ClN11O6S2
• Molecular Weight: 1012.7
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source