norbinaltorphimine

Overview

nor-Binaltorphimine (Norbinaltorphimine; NorBNI) is a selective, long-acting competitive antagonist of the κ-opioid receptor . nor-Binaltorphimine blocks κ-opioid receptor-mediated analgesic effects, and inhibits butorphanol-induced changes in κ-opioid receptor binding kinetics, desensitization and down-regulation. nor-Binaltorphimine suppresses specific opioid withdrawal symptoms, precipitates withdrawal behaviors in butorphanol-dependent rats, and serves as a molecular probe for studying κ-opioid receptor-agonist interactions. nor-Binaltorphimine is applicable to research related to neurological disorders such as pain.

Application

Products

Product Information

• Catalog No.: BP-20300
• CAS No.: 105618-26-6
• Molecular Formula: C40H43N3O6
• Molecular Weight: 661.79
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source