VU0467154

Overview

VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor ( mAChR ) , potentiating the response to ACh with pEC 50 s of 7.75, 6.2 and 6 for rat, human and cynomolgus monkey M4 receptor, respectively.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > mAChR

Product Information

• Catalog No.: HY-112209
• CAS No.: 1451993-15-9
• Molecular Formula: C17H15F3N4O3S2
• Molecular Weight: 444.45
• Purity: 99.23%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 1.39 mg/mL (3.13 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source