D-Lin-MC3-DMA

Overview

D-Lin-MC3-DMA (MC3) is a potent ionizable lipid used in lipid nanoparticle (LNP) formulations for delivering siRNA, mRNA, and DNA in gene therapy and RNA-based therapies. With a pKa of 6.44 , it facilitates endosomal escape by becoming protonated in acidic environments, making it ideal for intracellular delivery . MC3 is a key component in mRNA vaccines and non-viral gene delivery systems, available in reagent grade for research purposes.

Application

Drug Formulation > Lipids for Drug Delivery > Ionizable Lipid

Product Information

• Catalog No.: AP14387
• CAS No.: 1224606-06-7
• Molecular Formula: C43H79NO2
• Molecular Weight: 642.10
• Purity: ≥95%
• Availability: In Stock

Source

Original product source