IMP-1088

Overview

IMP-1088 is a potent human N-myristoyltransferases NMT1 and NMT2 dual inhibitor with IC 50 s of <1 nM for HsNMT1 and HsNMT2. IMP-1088 has a K d of <210 pM for HsNMT1. IMP-1088 efficiently blocks rhinovirus replication by blocking rhinovirus virus-encoded protein (VP0) N-myristoylation. IMP-1088 protects host cells from the cytotoxic effects of viral infection .

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-112258
• CAS No.: 2059148-82-0
• Molecular Formula: C25H29F2N5O
• Molecular Weight: 453.53
• Purity: 98.25%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (5.51 mM); Clear solution
• Availability: In-stock

Source

Original product source