PF-06733804 is a potent pan-Trk inhibitor in cell-based assays with IC 50 s of 8.4 nM, 6.2 nM and 2.2 nM for TrkA , TrkB and TrkC , respectively. Anti-hyperalgesic effect.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Trk Receptor
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