Sandoz 58-035

Overview

Sandoz 58-035 is a selective acyl-CoA:cholesterol acyltransferase ( ACAT ) inhibitor. Sandoz 58-035 inhibits this enzyme in intact cells and isolated microsomal fractions. Sandoz 58-035 blocks the esterification of exogenous vesicle-derived cholesterol and the incorporation of oleic acid into cellular cholesterol esters, reducing the formation and accumulation of cholesterol esters. Sandoz 58-035 causes a slight increase in cellular free cholesterol , and at high concentrations, it also causes a slight reduction in overall cellular protein synthesis. Sandoz 58-035 can be used in studies related to cellular cholesterol regulation.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Acyltransferase

Product Information

• Catalog No.: HY-112487
• CAS No.: 78934-83-5
• Molecular Formula: C30H47NOSi
• Molecular Weight: 465.79
• Purity: 99.34%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.37 mM); Clear solution
• Availability: In-stock

Source

Original product source