Acetoacetic acid sodium

Overview

Acetoacetic acid sodium is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Acetoacetic acid sodium induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase ( SOD ), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE , and low density lipoprotein receptor ( LDLR ), leading to triglyceride (TG) accumulation in hepatocytes. Acetoacetic acid sodium can be used to study metabolic diseases.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-112540B
• CAS No.: 623-58-5
• Molecular Formula: C4H5NaO3
• Molecular Weight: 124.07
• Purity: 98.0%
• Storage: -80°C, stored under nitrogen * The compound is unstable in solutions, freshly prepared is recommended.
• Solubility: ≥ 1.04 mg/mL (8.38 mM); Clear solution
• Availability: In-stock

Source

Original product source