IK1 inhibitor PA-6

Overview

IK1 inhibitor PA-6 (PA-6), a pentamidine analogue, is a selective and potent I K1 (K IR 2.x ion-channel-carried inward rectifier current) inhibitor, with IC 50 values of 12-15 nM for human and mouse K IR 2.x currents. IK1 inhibitor PA-6 (PA-6) elevates K IR 2.1 protein expression and induces intracellular K IR 2.1 accumulation. IK1 inhibitor PA-6 (PA-6) has the potential to treat atrial fibrillation and arrhythmia.

Application

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Product Information

• Catalog No.: HY-112544
• CAS No.: 500715-03-7
• Molecular Formula: C31H32N4O2
• Molecular Weight: 492.61
• Purity: 99.29%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (4.22 mM); Clear solution
• Availability: In-stock

Source

Original product source