Osoresnontrine

Overview

Osoresnontrine (BI-409306) is a potent and selective PDE9A inhibitor, with an IC 50 of 52 nM, and shows weak activity against other PDEs, such as PDE1A ( IC 50 , 1.4 µM), PDE1C ( IC 50 , 1.0 µM), PDE2A, PDE3A, PDE4B, PDE5A, PDE6AB, PDE7A, and PDE10A ( IC 50 all > 10 μM); Osoresnontrine can be used in the research of memory enhancement in CNS disorders.

Application

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Product Information

• Catalog No.: HY-112831
• CAS No.: 1189767-28-9
• Molecular Formula: C16H17N5O2
• Molecular Weight: 311.34
• Purity: 99.94%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (8.03 mM); Clear solution
• Availability: In-stock

Source

Original product source