15-keto-Prostaglandin E2

Overview

15-keto-Prostaglandin E2 (15-keto-PGE2) is an endogenous PGE 2 metabolite. 15-keto-Prostaglandin E2 inhibits STAT3 activation by binding to the Cys259 residue of STAT3 . 15-keto-Prostaglandin E2 binds to and stabilizes EP2 and EP4 receptors. 15-keto-Prostaglandin E2 inhibits the growth and progression of breast cancer cells. 15-keto-Prostaglandin E2 activates PPAR-γ and promotes fungal growth. 15-keto-Prostaglandin E2 disrupts glomerular vascularization during zebrafish development and reduces the surface area of the glomerular filtration barrier.

Application

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Product Information

• Catalog No.: HY-113205
• CAS No.: 26441-05-4
• Molecular Formula: C20H30O5
• Molecular Weight: 350.45
• Purity: 99.0%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source