15-Keto-prostaglandin E2-d 9

Overview

15-Keto-prostaglandin E2-d 9 is the d 9 labeled 15-keto-Prostaglandin E2 ( HY-113205 ). 15-keto-Prostaglandin E2 (15-keto-PGE2) is an endogenous PGE 2 metabolite. 15-keto-Prostaglandin E2 inhibits STAT3 activation by binding to the Cys259 residue of STAT3 . 15-keto-Prostaglandin E2 binds to and stabilizes EP2 and EP4 receptors. 15-keto-Prostaglandin E2 inhibits the growth and progression of breast cancer cells. 15-keto-Prostaglandin E2 activates PPAR-γ and promotes fungal growth. 15-keto-Prostaglandin E2 disrupts glomerular vascularization during zebrafish development and reduces the surface area of the glomerular filtration barrier.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Fungal Infection | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Renal Disease | Products > Disease Areas > Cryptococcal Infection | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Research Areas > Endocrinology | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > Endogenous Metabolite | Products > Signaling Pathways > Prostaglandin Receptor | Products > Signaling Pathways > STAT | Products > Signaling Pathways > PPAR | Products > Signaling Pathways > Fungal | Products > Signaling Pathways > Drug Metabolite

Product Information

• Catalog No.: HY-113205S
• CAS No.: 2738376-66-2
• Molecular Formula: C20H21D9O5
• Molecular Weight: 359.50
• Purity: 99.98%
• Storage: Solution, -20°C, 2 years
• Availability: In-stock

Source

Original product source