1-Methyladenine

Overview

1-Methyladenine is a gonad maturation-promoting regulator . 1-Methyladenine is produced in testes and ovarian follicle cells of starfish under the induction of gonad-stimulating substance (GSS). 1-Methyladenine promotes starfish oocyte maturation and spawning, and modifies bases that regulate DNA structure. 1-Methyladenine converts T-A base pairs in double-stranded DNA into non-disruptive T (anti)m1A (syn) Hoogsteen conformation. If this conformational base is not repaired in a timely manner, 1-Methyladenine transforms into cytotoxic DNA damage and blocks the replication process.

Application

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Product Information

• Catalog No.: HY-113306
• CAS No.: 5142-22-3
• Molecular Formula: C6H7N5
• Molecular Weight: 149.15
• Purity: 99.99%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 1.39 mg/mL (9.32 mM); Clear solution
• Availability: In-stock

Source

Original product source