Hederagenin (Standard) is the analytical standard of Hederagenin. This product is intended for research and analytical applications. Hederagenin is a triterpenoid saponin with orally active and antitumor activity. Hederagenin can inhibit the expression of iNOS , COX-2 , and NF-κB in cells induced by LPS stimulation. Hederagenin also increases ROS production in cancer cells, disrupts mitochondrial membrane potential, and induces apoptosis . Hederagenin also sensitizes cancer cells to Cisplatin ( HY-17394 ) and Paclitaxel ( HY-B0015 ), enhancing induced apoptosis . Hederagenin also has preventive potential against alcoholic liver injury.
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