12S-HHT

Overview

12S-HHT (12(S)-HHTrE) is an enzymatic product of prostaglandin H 2 (PGH 2 ) derived from cyclooxygenase ( COX )-mediated arachidonic acid metabolism. 12S-HHT is an endogenous ligand for BLT2 that fully activates BLT2 in vivo. 12S-HHT suppresses UV-induced IL-6 synthesis in keratinocytes, exerting an anti-inflammatory activity.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Leukotriene Receptor | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-113330
• CAS No.: 54397-84-1
• Molecular Formula: C17H28O3
• Molecular Weight: 280.40
• Purity: 98.4%
• Storage: Solution, -20°C, 2 years
• Availability: In-stock

Source

Original product source