12-HETE

Overview

12-HETE, a major metabolic product of arachidonic acid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-κB through the integrin-linked kinase (ILK) pathway.12-HETE has both anti-thrombotic and pro-thrombotic effects. 12-HETE is a neuromodulator.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-113439
• CAS No.: 71030-37-0
• Molecular Formula: C20H32O3
• Molecular Weight: 320.47
• Purity: 95.7%
• Storage: Solution, -20°C, 2 years
• Availability: In-stock

Source

Original product source