Actinonin

Overview

Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces . Actinonin inhibits aminopeptidase M , aminopeptidase N and leucine aminopeptidase . Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a K i of 0.28 nM. Actinonin also inhibits MMP-1 , MMP-3 , MMP-8 , MMP-9 , and hmeprin α with K i values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities.

Application

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Product Information

• Catalog No.: HY-113952
• CAS No.: 13434-13-4
• Molecular Formula: C19H35N3O5
• Molecular Weight: 385.50
• Purity: 98.37%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (12.97 mM); Clear solution
• Availability: In-stock

Source

Original product source