PF-04859989

Overview

PF-04859989 is a brain-penetrant, irreversible kynurenine aminotransferase (KAT) II inhibitor with IC 50 s of 23 and 263 nM for hKAT II and rKAT II. PF-04859989 is selective for KAT II over human KAT I, KAT III, and KAT IV ( IC 50 s of 22, 11, and >50 μM, respectively).

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Aminotransferases (Transaminases)

Product Information

• Catalog No.: HY-113967
• CAS No.: 34783-48-7
• Molecular Formula: C9H10N2O2
• Molecular Weight: 178.19
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source