NCGC00092410

Overview

NCGC00092410 is a potent, selective, and nonsugar glucocerebrosidase (GC) inhibitor, with an IC 50 of 31 nM. NCGC00092410 shows no activity against the related hydrolases at concentrations up to 77 μM. NCGC00092410, a GC chaperone, and increases the activity and lysosomal localization of glucocerebrosidase in mutant cell lines. NCGC00092410 can be used for the research of Gaucher disease.

Application

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Product Information

• Catalog No.: HY-114043
• CAS No.: 442898-34-2
• Molecular Formula: C21H27N3O2
• Molecular Weight: 353.46
• Purity: 98.10%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (5.88 mM); Clear solution
• Availability: In-stock

Source

Original product source