PF-00356231

Overview

PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 ( IC 50 =1.4 μM). PF-00356231 hydrochloride binds to MMP-12 and forms PF-00356231/MMP-12 complex. PF-00356231 hydrochloride shows potency against MMP-13 , MMP-8 , MMP-9 , MMP-3 with IC 50 s of 0.00065, 1.7, 0.98, 0.39 μM, respectively.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > MMP

Product Information

• Catalog No.: HY-114091A
• CAS No.: 766536-21-4
• Molecular Formula: C25H20N2O3S
• Molecular Weight: 428.50
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source