IRAK4-IN-4 (Compound 15) is an interleukin-1 receptor-associated kinase 4 ( IRAK4 ) inhibitor, with an IC 50 of 2.8 nM. IRAK4-IN-4 also inhibits cyclic GMP-AMP synthase ( cGAS ) with an IC 50 of 2.1 nM. IRAK4-IN-4 can be used for research of autoimmune diseases.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Arthritis | Products > Disease Areas > Rheumatoid Arthritis | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > IRAK | Products > Signaling Pathways > Cyclic GMP-AMP Synthase
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