L-163958

Overview

L-163958 is an efficient, orally active, balanced angiotensin II receptor ( AII receptor ) antagonist. L-163958 has balanced high affinity for AT1 and AT2 , with its IC 50 values being 0.16, 0.12, 0.50, and 0.64 nM in rabbit aorta (AT1), rat midbrain (AT2), human adrenal gland (AT1), and human adrenal gland (AT2), respectively. L-163958 has a strong inhibitory effect on the pressor activity in rats. L-163958 can be used for the study of hypertension and related cardiovascular diseases.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Hypertension | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Angiotensin Receptor

Product Information

• Catalog No.: HY-114284
• CAS No.: 168473-51-6
• Molecular Formula: C33H37BrFN5O6S
• Molecular Weight: 730.64
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source