HMG499

Overview

HMG499 is a potent and selective HMG-CoA reductase inhibitor with an IC 50 of 0.41 μM. HMG499 can prevent statins-induced accumulation of HMGCR, reduce serum cholesterol levels and decrease atherosclerosis.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Autophagy | Products > Research Areas > Metabolic Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > HMG-CoA Reductase (HMGCR) | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-114316
• CAS No.: 2416941-68-7
• Molecular Formula: C33H54O3
• Molecular Weight: 498.78
• Purity: 96.12%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (10.02 mM); Clear solution
• Availability: In-stock

Source

Original product source