Kira8

Overview

Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC 50 of 5.9 nM.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Glucose Metabolism | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > IRE1

Product Information

• Catalog No.: HY-114368
• CAS No.: 1630086-20-2
• Molecular Formula: C31H29ClN6O3S
• Molecular Weight: 601.12
• Purity: 98.90%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: 4 mg/mL (6.65 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source