Zetomipzomib maleate

Overview

Zetomipzomib (KZR-616) maleate, a first-in-class immunoproteasome inhibitor, selectively targets the LMP7 (IC 50 : 39/57 nM=hLMP7/mLMP7) and LMP2 (IC 50 : 131/179 nM=hLMP2/mLMP2) subunits of the immunoproteasome. Zetomipzomib maleate has the potential for the research of multiple autoimmune diseases.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Proteasome

Product Information

• Catalog No.: HY-114419A
• CAS No.: 2170983-62-5
• Molecular Formula: C34H46N4O12
• Molecular Weight: 702.75
• Purity: 99.84%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (2.96 mM); Clear solution
• Availability: In-stock

Source

Original product source