CP-339818

Overview

CP-339818 is a non-peptide Kv1.3 channel ( IC 50 = 200 nM) and Kv1.4 channel blocker. CP 339818 inhibits HCN channel with IC 50 s of 18.9 μM and 43.4 μM against HCN1 and HCN4 (high Cl - ). CP-339818 has significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels. CP-339818 selectively blocked Kv1.3, thereby inhibiting the activation process of human T cells. CP-339818 can be used to study the physiological functions of HCN and Kv channels.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Potassium Channel | Products > Signaling Pathways > HCN Channel

Product Information

• Catalog No.: HY-114540
• CAS No.: 185855-91-8
• Molecular Formula: C21H24N2
• Molecular Weight: 304.43
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source