Satigrel

Overview

Satigrel (E5510) is a potent inhibitor of platelet aggregation . Satigrel inhibits collagen- and arachidonic acid-induced platelet aggregation through preventing thromboxane A2 synthesis by selective inhibition of the target enzyme, PGHS1 , which exists in platelets. Satigrel inhibits PGHS1 ( IC 50 : 0.081 μM) and PGHS2 (IC 50 : 5.9 μM). Satigrel is against Type III PDE, Type V and Type II (IC 50 : 15.7 μM, 39.8 μM and 62.4 μM, respectively).

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Prostaglandin Receptor

Product Information

• Catalog No.: HY-114564
• CAS No.: 111753-73-2
• Molecular Formula: C20H19NO4
• Molecular Weight: 337.37
• Purity: 99.85%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (7.41 mM); Clear solution
• Availability: In-stock

Source

Original product source