LY302148 is a receptor ligand for 5-HT 1F . Compared to the E max of 5-HT, LY302148 behaves as a partial agonist for the 5-HT 1F receptor. In the [ 35 S]GTPγS binding assay targeting human 5-HT 1F receptors, LY302148 exhibits good potency with an EC 50 value of 5.23 nM. LY302148 can be used in the research of migraine.
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