BMS-192364 is targeting the G α -RGS interaction to produce an inactive Gα-RGS complex. BMS-192364 reduces urinary bladder contraction and exert RGS -agonist properties by increasing the action of GAPs on Gq proteins. BMS-192364 inhibits calcium flux.
Products | Products > Disease Areas > Hypertension | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > RGS Protein | Products > Signaling Pathways > Calcium Channel
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