Piericidin A

Overview

Piericidin A (AR-054) is a natural mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase . Piericidin A is also a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca) . Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer , insecticidal activity.

Application

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Product Information

• Catalog No.: HY-114936
• CAS No.: 2738-64-9
• Molecular Formula: C25H37NO4
• Molecular Weight: 415.57
• Purity: 99.83%
• Storage: Solution, -20°C, 2 years
• Availability: In-stock

Source

Original product source