MS437 is a potent TSH receptor ( TSHR ) stimulator with an EC 50 value of 13x10 -8 M. MS437 shows potent activation of G sα , G αq and Gα 12 and up-regulation of thyroglobulin (Tg), sodium iodine symporter (NIS) and TSHR gene expressions.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Endocrinology | Products > Signaling Pathways > TSH Receptor
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