SPR inhibitor 3

Overview

SPR inhibitor 3 (SPRi3) is a potent sepiapterin reductase (SPR) inhibitor. SPR inhibitor 3 (SPRi3) displays high binding affinity to human SPR in a cell-free assay ( IC 50 =74 nM) and efficiently reduces biopterin levels in a cell-based assay (IC 50 =5.2 μM). SPR inhibitor 3 (SPRi3) reduces neuropathic and inflammatory pain through a reduction of BH4 levels.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Carbonyl Reductase

Product Information

• Catalog No.: HY-115510
• CAS No.: 1292285-54-1
• Molecular Formula: C14H18N2O3
• Molecular Weight: 262.30
• Purity: 99.01%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (9.53 mM); Clear solution
• Availability: In-stock

Source

Original product source