Calmodulin antagonist-1

Overview

Calmodulin antagonist-1 (A-5) is a calmodulin (CaM) antagonist. Calmodulin antagonist-1 inhibits calmodulin-activated Ca 2+ -phosphodiesterase (PDE) (IC 50 =66 μM). Calmodulin antagonist-1 also inhibits trypsin-treated Ca 2+ -PDE (IC 50 =560 μM) in a competitive fashion with respect to cyclic GMP.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Calmodulin

Product Information

• Catalog No.: HY-115745
• CAS No.: 78957-84-3
• Molecular Formula: C14H18Cl2N2O2S
• Molecular Weight: 349.28
• Purity: 98.0%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (7.16 mM); Clear solution
• Availability: In-stock

Source

Original product source