GPVI antagonist 2 (Compound 1) is a potential antagonist of Glycoprotein VI ( GPVI ). IC 50 values of GPVI antagonist 2 are, respectively, 0.35 μM for collagen , 0.80 μM for CRP, 195.2 μM for convulxin and 81.38 μM for thrombin . Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 2 is a promising antiplatelet agent.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Glycoprotein VI
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