PROTAC HSP90 degrader BP3

Overview

PROTAC HSP90 degrader BP3 is a potent and selective degradation of HSP90 in a CRBN -dependent fashion. PROTAC HSP90 degrader BP3 has a certain degradation effect on HSP90 protein in MCF-7 cells ( DC 50 =0.99 μM). PROTAC HSP90 degrader BP3 inhibits the growth of breast cancer cell. PROTAC HSP90 degrader BP3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. (Pink: HSP90 ligand ( HY-W437598 ); Blue: Cereblon ligand ( HY-10984 ); Black: linker).

Application

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Product Information

• Catalog No.: HY-115997
• CAS No.: 2669072-88-0
• Molecular Formula: C32H29ClN8O5
• Molecular Weight: 641.08
• Purity: 99.54%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source