PDEB1-IN-1 (Compound 12b) is the derivative of Cilomilast ( HY-10790 ), and serves as an inhibitor for TryPanosoma Brucei PDEB1 ( TbrPDEB1 ) with an IC 50 of 0.95 μM. PDEB1-IN-1 inhibits the proliferation of T. Brucei with an EC 50 of 26 μM.
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