Conoidin A

Overview

Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. Conoidin A covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC 50 of 23 μM. Conoidin A also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII). Conoidin A has antioxidant, neuroprotective effects and can be used for the research of ischaemic heart disease.

Application

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Product Information

• Catalog No.: HY-116090
• CAS No.: 18080-67-6
• Molecular Formula: C10H8Br2N2O2
• Molecular Weight: 347.99
• Purity: 99.32%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.43 mg/mL (4.11 mM); Clear solution
• Availability: In-stock

Source

Original product source