N-Acetyldesloratadine (SCH-37370) is a potent, orally active dual antagonist of platelet-activating factor (PAF) and histamine . N-Acetyldesloratadine inhibits PAF-induced aggregation of human platelets, with an IC 50 of 0.6 µM. N-Acetyldesloratadine can be used for the study of allergic diseases, such as asthma.
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