MS453

Overview

MS453 is a potent and highly selective SETD8 inhibitor with an IC50 value of 804 nM. MS453 specifically modifies a cysteine residue close to the inhibitor binding site. MS453 is selective for 28 other methyltransferases. The crystal structure of MS453 reveals its binding mode to SETD8, providing an atomic-level view for the development of high-quality chemical probes for SETD8.

Application

Products | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Others | Products > Signaling Pathways > Histone Methyltransferase

Product Information

• Catalog No.: HY-116255
• CAS No.: 2059892-29-2
• Molecular Formula: C20H27N5O3
• Molecular Weight: 385.46
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source