RP-69758 is a potent and selective non-peptide cholecystokinin-B ( CCK B )/ gastrin receptor antagonist. RP-69758 exhibits >200-fold selectivity for CCK B over CCK A receptors. RP-69758 antagonizes CCK-8-induced neuronal firing in rat hippocampal slices. RP-69758 inhibits Pentagastrin ( HY-A0261 )-induced gastric acid secretion in the rat. RP-69758 can be used for neurological disorders and gastrointestinal disease research .
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